Oprah Winfrey may have stepped away from Weight Watchers, but she鈥檚 not staying out of the conversation about weight.

The mogul will host 鈥渁 sit-down conversation around the radical impact of prescription weight loss medications鈥 in 鈥淎n Oprah Special: Shame, Blame and the Weight Loss Revolution,鈥 scheduled to air on ABC on March 18 and the next day on Hulu.

The special will take place in front of a live audience with medical experts to explore 鈥減revailing questions and concerns surrounding the impact on our health care, economy, lifestyle and culture,鈥 a press release for the event states.

鈥淚t is a very personal topic for me and for the hundreds of millions of people impacted around the globe who have for years struggled with weight and obesity,鈥 Winfrey said in the announcement. 鈥淭his special will bring together medical experts, leaders in the space and people in the day-to-day struggle to talk about health equity and obesity with the intention to ultimately release the shame, judgment and stigma surrounding weight.鈥

In October, Winfrey hosted her Oprah Daily鈥檚 鈥淭he Life You Want Class: The State of Weight鈥 and talked about sharing her weight journey over the years.

鈥淢y highest weight was 237 pounds,鈥 she said. 鈥淚 don鈥檛 know if there is another public person whose weight struggle has been exploited as much as mine over the years.鈥

Craig Erwich, president of Disney Television Group, expressed excitement about the project.

鈥淚 can think of no one better to lead this meaningful conversation about such a critical issue that touches all of our lives.鈥